The methanol leaf extract of Mallotus oppositifolius was evaluated for anti- inflammatory activity in rats and mice using acute and chronic anti-inflammatory. Mallotus oppositifolius is widely distributed and occurs from Senegal east to Ethiopia and south to Angola and Mozambique, and also in Madagascar. Biochem Res Int. ; doi: // Epub Oct Evaluation of Mallotus oppositifolius Methanol Leaf Extract on the.

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Das Pflanzenreich 4, 7: The stems or the twigs are chewed fresh, or dried for later use. Potentials of Mallotus oppositifolius for agroforestry and land management in southeastern Nigeria.

The rats were fasted overnight before experimentation but were allowed free access to water. Field guide to the moist forest trees of Tanzania. The extract also showed in vitro concentration-dependent antioxidant activity following the 1,1-diphenylpicryl-hydrazyl DPPH and ferric reducing assays. With on-going researches in diabetes and oral hypoglycaemic agents OHAthe management of DM is still a global problem. Table 2 shows the effect of the extract on the liver MDA levels of diabetic rats.

Mallotus oppositifolius is widely distributed and occurs from Senegal east to Ethiopia and south to Angola and Opplsitifolius, and also in Madagascar.

Alloxan, from the literature, has been shown to cause hyperglycaemia in laboratory animals due to increased oxidative stress by elaborated free radicals [ 12 ], thus a model for type 1 diabetes studies.

The mixtures were filtered with Whatman number 1 oppositicolius paper. Reactive oxygen species ROS have been implicated in many pathologies such as heart diseases, cancers, arteriosclerosis, diabetes mellitus, and arthritis [ 22 ].


High blood glucose levels not only increase the production of reactive oxygen species Oppositifoliud but also affect antioxidant activities of ROS scavenging enzymes [ 67 ]. The extract decreased the blood glucose levels of experimental rats significantlyin a dose-dependent manner Table 1.

Mallotus oppositifolius Article Title: Clinical and Experimental Pharmacology and Physiology 33 1—2: Bioactive components of the leaf extracts of M.

Differences between the groups were separated by post hoc LSD.

Mallotus oppositifolius

The seed is a special soup thickener in the region. The extract was not toxic. The results show that the levels decreased in a dose-dependent manner. The ground leaves in salted water are applied to snakebites and the extract is also drunk for this purpose. Journal of Ethnopharmacology The authors declare that there is no conflict of interests as per this work, the project was not funded by any organization, and appropriate acknowledgments have been given to those deserving.

The results showed that MP significantly reduced the blood glucose and was found to possess significant antioxidant potentials in vitro both in the DPPH and the ferric reducing assay.

Mallotus oppositifolius – Useful Tropical Plants

MP is also claimed to have antidiabetic activity by local healers in the South-East area of Nigeria. Total cholesterol levels in diabetic rats treated with various doses of MP extracts. Therefore we selected and evaluated the methanol leaf extract of MP for its claimed antidiabetic potentials considering also, its effect on total cholesterol and biomarkers of oxidative stress in vivo and in vitrorespectively.


It is deep-rooting and has a root: One important area in diabetes management receiving particular attention today is that of herbal hypoglycaemic agents. An infusion of the roots together with the seeds of Aframomum melegueta K. Several factors such as dyslipidemia or hyperlipidemia which are involved in the microvascular and macrovascular complications as well as hyperglycemia are associated with the diabetes disease which is the major cause of morbidity and death [ 4 ].

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A leaf or stem bark infusion is taken to expel tapeworms and to treat diarrhoea. Click on “show more” to view them. Introduction Diabetes mellitus DM is a multifactorial syndrome resulting from a variable interaction of hereditary and environmental factors. Subscribe to Table of Contents Alerts. Antiparasitic activities of medicinal plants used in Ivory Coast.

West African Plants – A Photo Guide – Mallotus oppositifolius (Geiseler)

Mallotus comprises about species, which all occur in the Old World tropics, mainly in Asia and Oceania. The yield of the extract was 2. Antifungal property and phytochemical screening of the crude extracts of Funtumia elastica and Mallotus oppositifolius.

Malkotus, close correlations between cholesterol levels in blood and the diabetes have been previously reported [ 2728 ].

A decoction of the aerial parts was taken as an ordeal poison.